Acidif 90 Tablets

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Food supplement based on L-methionine and concentrated dry extract of Canadian cranberry with high titration of proanthocyanidins.
Helps promote correct functionality; of the urinary tract, creating unfavorable conditions for bacterial development and proliferation. It comes in retard tablets with gradual release and with a gastroprotective coating. There ò optimizes tolerability; and guarantees a constant release of its components over time.
L-Methionine
It is part of the essential amino acids and, as such, è an important constituent of the human organism. L-Methionine, which our body does not have; capable of producing, but must be introduced from the outside, è the only essential amino acid that contains sulfur in its formula. Availability of L-Methionine (as a sulfur donor) in quantities sufficient, è the necessary condition for the biosynthesis of cysteine, a sulfur amino acid. A large number of Gram-negative bacteria is able to alkalize the urine by enzymatic degradation of urea, thus determining; favorable growth conditions. The maintenance of a physiological pH obtained by the action of L-methionine, manages to create unfavorable conditions for bacterial colonization.
Cranberry
Studies recent have focused on the antibacterial effects of Canadian cranberry (Vaccinium macrocarpon - cranberry) aimed at adhesiveness; of some bacteria to the urinary epithelium. Women suffering from recurrent urinary infections appear to be particularly sensitive to the adhesion of uropathogenic bacteria. The uropathogenic strains rely on the adhesion of type P fimbriae to allow colonization and the related infectious process. According to these studies, cranberry proanthocyanidins prevent the adhesion of type P fimbriae of uropathogenic E. coli strains.

Ingredients

	for 1 tablet
L-methionine	400 mg
Cranberry Canadian cranberry concentrated dry extract 90 %	40 mg
Other ingredients: anti-caking agents: microcrystalline cellulose; hydrogenated and non-hydrogenated vegetable oils; silicon dioxide; talc; polydextrose; calcium phosphate; maltodextrin; coating agents: hydroxypropylmethylcellulose; hydroxypropylcellulose; shellac; dye: E 124.

Mode à for use
We recommend taking one tablet twice a day: 1 tablet in the evening before going to bed and 1 tablet in the morning upon waking up.

Warnings
Do not exceed the recommended daily dose.
Keep out of the reach of children under three years of age.
Supplements are not intended as a substitute for a varied diet.
For pregnant or lactating women and children it is recommended to seek medical advice.

Format
Pack of 90 tablets of 865 mg.

Cod. 1013.

Bibliography
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- Compendium Suisse des m é dicaments (Acimethin drug data sheet) - 2003.
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- Walker E et al - Cranberry juice concentrate: UTI prophylaxis - J.Fam.Pract. 1997; 45: 167- 8.
- Goodfriend R - Reduction of bacteriuria and pyuria using cranberry juice. - JAMA 1994; 272: 588.
- Howell AB et al - Inhibition of the adherence of P-fimbriated E.Coli to uroepithelial-cell surfaces by proanthocyanidin extracts from cranberries - N. Engl. J. Med 1998; 339: 10856.
- Ahuia S. - Loss of fimbrial adhesion with the addition of Vaccinum Macrocarpon to the growth medium of P-fimbriated E.coli - J. of Urology 1998; 159: 559-62.
- Ottarian SG - Medicinal herbal therapy: a pharmacist's view. Ports mouth, NH: Nicoln Fields Pub., 1999.
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