Description
Medical device useful for facilitating mobility, counteracting the physiological aging of the connective tissue, whose therapeutic treatment primary È consisting of the following functions:
1. Barrier effect.
2. Activities; lubricant.
3. Mechanical support in case of pharmacological therapy in progress.
We recommend the use of MD-TISSUE by qualified health personnel, in private or public health structures to:
- create a defense barrier against free radicals;
- counteract the physiological aging of the connective tissue;
- relieve localized pain caused by movement.

Modality À of use
MD-TISSUE pu Ò be used alone or associated with all other medical devices belonging to the same line, in order to create a personalized treatment based on the individual clinical picture. firming of the subcutaneous connective layer, MD-TISSUE should preferably be combined with MD-MATRIX (eg MD-TISSUE 2 vials, MD-MATRIX 1 vial / treatment). be used in patients requiring collagen supplementation or topical anti-aging treatment.

Therapeutic protocol :
2 treatments for the first 2 weeks, 1 treatment up to improvement of symptoms (on average 8-10 sessions). Eventually you can Ò continue with 1 treatment every other week for a maximum of 10 sessions.
Chronic diseases: continue with 1 treatment a week for one month until symptoms improve, and then with 1 treatment per month.

& bull ; Intradermally: the area of application must be aseptic;
Microinjections : introduce the needle at a shallow depth; of 1-3 mm, carry out microinjections of 0.2 ml & ndash; 0.3 ml in correspondence with the tissue to be treated.
Tunneling: 0.3 ml are applied along the wrinkle using the tunneling technique. Insert the needle almost tangential along the entire length of the area, then inject and at the same time withdraw the needle, while applying the product in a fan pattern.

& bull; Periarticular route: the area of application must be aseptic, introduce the needle perpendicular to the skin plane at a depth; of 2-4 mm, carry out micro-injections of 0.3-0.5 ml.

Modalit À of administration :
For this use of the medical device we recommend the use of the following materials and accessories:
& bull; Material to ensure skin asepsis: disposable glove, iodine-based solution, alcoholic solution, sterile gauze, ethyl chloride-based skin spray.
& bull; Microinjection needles: sterile 27G, 4mm.
& bull; Tunneling needles: sterile 30 G, 13 mm.
& bull; Syringes: 5 or 10 cc, according to the quantity; of solution to inject.

Components
Collagen of porcine origin.
Excipients: ascorbic acid, magnesium gluconate, pyridoxine hydrochloride, riboflavin, thiamine hydrochloride, NaCl, water injectable.

Warnings
Single use.
It is not; no cases of hypersensitivity have been reported.
Contains collagen of animal origin of porcine species. Patients with known hypersensitivity component or excipients must be previously subjected to injection testing in the arm and observed for one hour. be due to the mechanical effect of the needle or a skin reaction.
Application may cause burning / painful symptoms at the injection sites, which generally resolve within 5-10 minutes after the end of treatment.
È skin cleansing / disinfection required before and after application.
Any pyogenic bacteria may produce abscess in the injection area.
Keep out of the reach and sight of children.
Do not use after expiration.
Use the product immediately after opening.
Do not use if the seal is broken or tampered with.
After opening, the contents of the vial must be injected immediately.
Do not use in in case of damage to the packaging.

Storage
Store at a temperature of 2 & deg; C and 30 & deg; C, protect from sunlight and frost.
The date of expiry date refers to the product in unopened package, correctly stored.

Format
Box of 5 sterile vials of 2 ml