Night Cream Fillerina 12 Double Filler

Nourishing and restorative, with double filler effect. To be used by alone or in combination with other Fillerina preparations.
In 50ml tube.
Dosages: Grade 3, Grade 4 and Grade 5.

DOUBLE EFFECT FILLER
As we age the quantity of Acid Skin hyaluronic acid gradually reduces, causing imperfections such as wrinkles, expression and aging lines and loss of volume (emptying, skin depressions, etc.) in particular on the cheekbones, cheeks and lips. In Fillerina 12 Double Filler a mixture of 12 Hyaluronic Acids of various sizes and molecular weights is used, particularly effective in penetrating the skin layers (ex-vivo test through Franz Cells) to favor tissue filling and plumping. Hyaluronic Acids with filler effect have molecular weights ranging from 400 to two million Dalton, and owe their remarkable filling function to the ability to bind water molecules up to 1000 times their weight (Filler Effect 1). Hyaluronic acid is classified as a glycosaminoglycan as its molecule, unbranched, is made up of the repetition of disaccharide units composed of two molecules, Glucuronic Acid and Acetyl Glucosamine. The formulation innovation of Fillerina 12 Double Filler consists in providing the skin with these two fundamental precursors of hyaluronic acid for the endogenous production of the same by the dermal cells and substantially contributing to the filling mechanism from the inside (Effect Filler 2).
The AQP3 complex, formed by three molecules (Acetyl Hexapeptide-37, Glyceryl Glucoside, is inserted into the skin tissues to form the natural filler substance with hyaluronic acids). , Galactoarabinan) which favor the formation of â € œacquaporinsâ € or â € œchannelâ € proteins on the cell membrane of the keratinocytes and fibroblasts of the skin allowing the very fast flow of water molecules inside and outside the cells. Among the aspects of skin aging there is the impoverishment of the essential substances for the support and elasticity of the skin: Collagen and Elastin. The loss and reduction of collagen in the dermis results in a lower thickness and lower density of the extracellular matrix with a consequent increase in wrinkles, depressions and loss of volume. In the formula of Fillerina 12 Double Filler there are 3 molecules of Collagen with different molecular weights (2,000, 12,000 and 300,000 Dalton) able to favor the density of the extracellular matrix, and improve the filling in synergy with Hyaluronic Acids. There are also two molecules of Elastin with differentiated molecular weights of 1,400 and 2,200 Dalton which compensate for the physiological decrease by restoring elasticity and plasticity to the skin. The formula is completed by the specific component Matrifull (Palmitoyl Tetrapeptide-38).

RESTRUCTURING, OXYGENATING EFFECT
The formula Fillerina 12 Double Filler contains the complex of 7 molecules Plate- Like, synthetic growth factors but similar to endogenous molecules, with marked regenerative properties capable of carrying out a deep restructuring effect on the skin, favoring the reconstitution of skin structures such as collagen fibers, elastic fibers and extra-cellular matrix. The presence of Tropaeolum Majus Extract favors the transport of oxygen to the skin tissues, reactivating the cellular oxygenation mechanism and improving the uniformity and color of the skin, for a clear and radiant complexion. The presence of ATP and Ribose increases the cellular energy charge.

TRANSDERMAL TECHNOLOGY WITH 5 ENHANCERS
The skin is difficult to permeate: to ensure that Hyaluronic acids and the other functional molecules of Fillerina penetrate its different levels Labo researchers have developed a Transdermal Technology (Swiss Patent CH 711 466) which is based on the low molecular weight of the active substances: it becomes the fundamental condition for their penetration into the skin layers to which their real filling effectiveness is linked. All functional molecules are also supported by the presence of penetration facilitators, or enhancers. The five enhancers present in Fillerina 12 Double Filler are five glycols, substances that improve the absorption of functional molecules in the epidermis and dermis: Pentylene Glycol, Decylene Glycol, Caprylyl Glycol, Propylene Glycol and Butylene Glycol.

GRADE 3: Initial expression lines and lines. First aging wrinkles and micro-relief with discontinuous regularity. Principle of depression and tissue emptying. Skin with decreasing thickness, density and plasticity. First signs of subsidence. Need for more volume on cheekbones and lips.

Warnings
External use - Dermo-cosmetic treatment - Avoid contact with eyes - Do not ingest - Do not inject - Keep out of reach of children - Keep away from sources of light and heat.

Format
Tube 50ml
Dosage: Grade 3.